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@beritaopini: Kenaikan Gaji ASN, TNI, dan POLRI pada RAPBN 2024 #pns #berita

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Wednesday 30 August 2023 16:24:12 GMT
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what's your favorite neurotransmitter? source footage from That Chemist Tiny Motor Proteins, Dr. G Bhanu Prakash Animated Medical Videos Molecular Motors : Kinesin, Dynein and Myosin (Animation), Single Cell Animation Kinesin: The Motor Protein That Powers Your Cells!, Kelly Frankel Locomotion of the Kinesin Motor Molecule, Thom Leach Kinesin Walking Animation | 3D Molecular Motor with Cargo review from Hayashi K, Sasaki K. Number of kinesins engaged in axonal cargo transport: A novel biomarker for neurological disorders. Neurosci Res. 2023 Dec;197:25-30.
what's your favorite neurotransmitter? source footage from That Chemist Tiny Motor Proteins, Dr. G Bhanu Prakash Animated Medical Videos Molecular Motors : Kinesin, Dynein and Myosin (Animation), Single Cell Animation Kinesin: The Motor Protein That Powers Your Cells!, Kelly Frankel Locomotion of the Kinesin Motor Molecule, Thom Leach Kinesin Walking Animation | 3D Molecular Motor with Cargo review from Hayashi K, Sasaki K. Number of kinesins engaged in axonal cargo transport: A novel biomarker for neurological disorders. Neurosci Res. 2023 Dec;197:25-30. "In neurons, anterograde transport is characterized by the trafficking of synaptic materials, synthetized in the cell body, along axons and up to the synaptic terminals by kinesin motor proteins. Kinesin is a motor protein that processively moves mainly in the plus-end direction of microtubules by obtaining energy through ATP hydrolysis (Hirokawa et al., 2009, Vale, 2003). In contrast, the molecular motor known as dynein moves towards the minus end of the microtubule (Vale, 2003). Dynein functions to transport cargo in the direction opposite to that of kinesin, heading towards the microtubule's minus end. This allows for efficient multi-directional transport within the cell. Dynein and kinesin work in concert to facilitate complex intracellular transport processes. It is known that there are 45 types of kinesin superfamily members in mammalians such as humans and mice (Hirokawa et al., 2010). Among them, KIF1A is a kinesin that transports synaptic vesicle precursors, and it is known that mutations in KIF1A can cause excessive transport of synaptic vesicle precursors and transport disorders, leading to abnormalities in synapse formation (Anazawa et al., 2022, Chiba et al., 2019, Niwa et al., 2016). As a result, the mutations in KIF1A lead to severe neurodegenerative diseases (Gabrych et al., 2019, Guedes-Dias and Holzbaur, 2019)." #neuroscience #neurology #biochemist #metabolism #adventcalendar
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