@gorillamind: Can you naturally produce Creatine? Yes actually, Creatine is produced naturally in the body! But, most people will burn through upwards of 45% of their daily methylation capacity just to endogenously synthesize around 1 gram of Creatine. Most people overlook how crucial creatine is for neurological support and methylation balance. For those genetically predisposed to impaired methylation (which is incredibly common), and/or don’t get enough Creatine from their diet (near impossible for most), that process can become wildly inefficient. This can elevate homocysteine levels and impair folate metabolism, factors linked to cardiovascular risk, brain fog, and slower recovery, especially when left unaddressed. Supplementing with 5 grams of creatine daily has been shown to lower plasma homocysteine by almost 50 percent in those with the most significant methylation impairing MTHFR polymorphism (homozygous for C677T of MTHFR). Creatine supplementation in those who would benefit and otherwise don’t get enough from diet alone (most people), may reduce the endogenous demand (pulling valuable resources from other processes), and support not just physical performance, but also cognitive and cardiovascular health. Yes, creatine helps with muscle size, strength, and exercise performance. But its total value goes way beyond that.

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Tuesday 08 July 2025 04:26:09 GMT