@limmereducation: Anaphylaxis usually starts after an antigen enters the body again. The first exposure makes IgE antibodies that stay inactive—until the next time. Then mast cells and basophils release histamine, triggering a reaction. It might be mild or full-blown anaphylaxis. Fun fact: morphine can cause histamine release too. Mast cells release histamine, causing vessels to dilate and leak fluid—dropping BP and reducing preload. It’s like poking holes in a firehose. This drop leads to shock and swelling (angioedema). Histamine fades fast, but leukotrienes stick around longer, tightening airways and worsening anaphylaxis. Anaphylaxis can hit in seconds—faster onset usually means worse symptoms. Early signs? Sense of doom, hoarse voice, itchy throat, rash, hives, and swelling. Watch for airway issues like stridor. GI symptoms (nausea, vomiting, diarrhea) and low BP lead to shock. Act fast—untreated, it can progress to collapse. #anaphylaxis #emt #NREMT #NREMTPrep #nremtexam #paramedic #futureemt #aemt #medical #paramedicstudent #emergencymedicine #ems #prehospitalcare #emtschool

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Tuesday 15 July 2025 23:34:03 GMT