ianisfun
Region: US
Tuesday 29 July 2025 23:41:37 GMT
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Brandt BayLeif :
“With out the addiction risk” said by every other painkiller ever
2025-07-30 01:50:04
1951
jorjor..wel :
fun fact! you’re not assigned to placebo usually for drug trials-you’re assigned ‘standard treatment’ (eg whatever normal pain killing looks like for that procedure) which keeps a statistical baseline but doesn’t unnecessarily torture study participants
2025-07-30 00:50:39
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Ryan Is Not Cheeks :
I’ve had an unremitting headache originating from my jaw for 10 years so this is the best news I’ve ever heard
2025-07-31 08:16:09
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Nic :
sorry, lil pedantic thing,but as a voltage-gated sodium channel researcher, you would read "Nav1.7" as Nav (rhymes with "ave-" in "average") 1.7. The "v" refers to them being voltage-gated, but there are other types of voltage-gated channels (Kv [potassium] channels for example), so ya can't call them "v1.7". But sick video, it's exciting stuff!
2025-07-30 01:56:21
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August :
I’ve seen that show where they say there’s no addiction risk (there always is)
2025-07-30 07:57:21
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Miku :
NOOO PLS DON'T TAKE OPIOIDS 💔
2025-07-30 18:28:56
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Salmoon :
It’s bizarre how opioids are so prevalent in the US. I have gone through multiple very painful surgeries, and never got any for pain. The only time I got any opioid at all was an IV one when I nearly ripped my arm off and they needed it so I wouldn’t pass from shock
2025-07-30 14:23:13
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vanczosyn :
I’ll be great in 20 years when the patent expires
2025-07-30 05:41:24
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ferg4096 :
without the addiction risk? I've seen this one before.
2025-07-31 14:19:17
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A :
The problem with painkillers is that you almost always become reliant on them
2025-07-30 19:52:42
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Potatoes are good :
Couldn’t it just be done on people experiencing chronic pain? My dad has chronic back pain due to something with his nerve being like permanently pinched/agitated. If he moves wrong he can induce a spasm that’ll last a few min of extreme pain. He already regularly gets spinal injections, I’d bet he would endure a spasm or two just to see if this would help him.
2025-07-30 11:16:13
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Pedro Hierro :
This Is Not Going To help for chronic pain, bc pain is not only dependent on signals but on pain cognition and interpretation on the brian (aka nociplastic)
2025-07-30 23:43:42
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AtomSmasher99 :
but without the addiction risk how will the pharmaceutical companies make money
2025-07-30 02:00:18
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Kelly Jean :
I have Erythromelalgia and no painkillers work for me, this could be a huge game changer!
2025-07-30 15:38:43
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DaveTheResident :
I believe in this study the experimental group also had access to Tylenol and ibuprofen as a rescue drug. The frequency of use was not recorded. Big confounding variable
2025-07-30 19:21:29
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TinPUEBLO :
Wow! This is amazing news.
2025-07-29 23:46:34
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Jrojross :
Only $2,000 a month
2025-07-30 17:52:39
1
Andy :
Is this somewhere along the lines of the way tetrodotoxin works
2025-07-30 04:12:37
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malte :
the v stands for voltage-activated. Nav1.7 doesn't mean that the potential is 1.7 Volts but that it's a voltage activated sodium channel, 7 standing for the 7th gene we've figured out
2025-07-30 15:24:31
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Trevor :
so you’re telling me super soldiers that can’t feel the pain without addiction ??
2025-07-30 07:05:26
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Heartqueefer :
I'll believe it when I see it
2025-07-30 19:01:37
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Cory :
We’ll see if that makes any difference anytime soon. The first hurdle is making it affordable and getting it covered by insurance. I work in pharmacy and have received a few prescriptions for Journavx already, but we haven’t dispensed any due to the cost and it not being covered
2025-07-30 10:06:09
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Hoskingc :
wait isn't the normal way to measure pain in pain killer trials to give the intervention to one group, placebo to other, then offer traditional pain meds as top ups and measure how much trad pain meds each group used? I don't think patients end up lingering in pain.
2025-07-30 03:27:08
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vyllix :
I don't know how I feel about this being on my fyp after watching The Lazarus Project 😂
2025-07-30 10:39:06
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TheMedChemPhD :
Love it!!
2025-07-31 15:17:24
0
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