@umarchatterjee: 🚨 OCD is a neurobiological BRAIN disorder, FULL stop--and here's how we're treating it. 👏🏾 🧠 EVERYTHING YOU NEED TO KNOW ABOUT DBS & TMS: Precision Targeting, Biotypes, & the Brain Basis of OCD & Depression with Dr. Martijn Figee 🎯 Ep. 48 of A Chat with Uma is out now!🌟 On ep. 48, I sit down with psychiatrist–neuroscientist Dr. Martijn Figee—a groundbreaking pioneer in neurostimulation (e.g. DBS, TMS) for psychiatric disorders, especially OCD & depression—for a clear, grounded tour of circuit‑based psychiatry, explaining how & why the brain can change (in minutes!) when the right circuit is engaged. We unpack deep brain stimulation (DBS) surgery & transcranial magnetic stimulation (TMS), what “target selection” actually means, & how phenotyping (motor, cognitive, & negative‑affect circuits) guides targeting. We discuss access & eligibility, what insurers & clinicians look for, when to choose TMS first, & how accelerated TMS paired with ERP can fast‑track change. We bust myths about the neurobiology & brain basis of mental illnesses & share biotyping work designed to match people to the right target. This episode shares everything you need to know about DBS & TMS from *the* world's expert! Topics discussed include👇🏾 🎯Who is the Martijn behind the titles, really? 🎯From Amsterdam to DBS: imaging arrives, early OCD DBS cases, & changes in minutes 🎯Circuit basics: motor–cognitive–limbic loops across OCD, Tourette, depression 🎯Comorbidity vs. one driver: how untreated OCD breeds depression—& why it changes the treatment plan 🎯Phenotyping (negative affect vs compulsion/motor vs cognitive) to pick a target 🎯TMS before DBS? Standard vs accelerated TMS & pairing every session with ERP; access & insurance 🎯DBS candidacy & access 🎯Targeting, not guessing: ALIC/internal capsule, STN, BNST & fiber‑map guidance pushing outcomes toward ~80% 🎯Biotyping with in-scan tasks: motor/cognitive/limbic dominance; what scans can (& can’t) diagnose—yet 🎯Myth‑busting: OCD ≠ an “amygdala disorder” ☀️ Subscribe, rate, review, & SHARE to support the show 🫶🏾 🔗 Link in bio, or search ‘A Chat with Uma’ on all platforms to listen! #OCD #MentalHealth #mentalillness #dbs #biology #psychology #psychiatry

Uma R. Chatterjee, M.S., MHPS

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Sunday 03 August 2025 23:10:03 GMT