@babies_after_35: Fever during pregnancy as a risk factor for neurodevelopmental disorders: results from a systematic review and meta-analysis: Additional evidence supported the association between fever during pregnancy and increased risk for NDD in offspring. Careful monitoring should be considered for children born from mothers with a febrile episode during pregnancy (specifically during the first trimester). Maternal fever during pregnancy and offspring attention deficit hyperactivity disorder: The results indicate that maternal fever in early pregnancy may be a risk factor for ADHD, and particularly for inattention problems. This risk is neither mitigated nor inflated by use of acetaminophen. Infection and Fever in Pregnancy and Autism Spectrum Disorders: Findings from the Study to Explore Early Development: These findings of an association between maternal infection with fever in the second trimester and increased risk of ASD in the offspring suggest that the inflammatory response to the infectious agent may be etiologically relevant. Prenatal fever and autism risk: ASD risk appears to increase with maternal fever, particularly in the second trimester. Risk magnified dose dependently with exposure to multiple fevers after 12 weeks' gestation. Our findings support a role for gestational maternal infection and innate immune responses to infection in the pathogenesis of at least some cases of ASD. #autismawareness #adhd #tylenol

Shannon M. Clark, MD, FACOG

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Wednesday 24 September 2025 19:54:20 GMT